Agents of STRIKE
The Incapacitating Cartridge Emitting Railgun (ICER) was created as a less-than-lethal option by SCI-TECH. It magnetically fires a dendrotoxin payload designed to immediately incapacitate a full-grown human adult with one shot, even through clothing.
ICERs are fairly safe, although if used against someone who is especially weak or small in size they are possibly fatal. It is possible to kill with ICERs if they are used repeatedly on the same target in a short period of time (more than half a dozen shots), as the dendrotoxin will build up and stop the nervous system.
Against extranormal targets, one or two shots may not immediately incapacitate and a field agent may be reluctant to fire again, for fear that repeated shots may kill the target due to delayed onset of the dendrotoxin. The agent is reminded to use their best judgment and trust their instincts, and decide if preserving the life of the extranormal target is worth the risk to their own life or the lives of others. ICERs are a useful LTL tool for SHIELD agents but lethal force is still sometimes a requirement to resolve a crisis situation.